Artigos Publicados em Revistas Cientificas - FAMED: Recent submissions

  • The association among literacy, numeracy, HIV knowledge and health-seeking behavior: a population-based survey of women in rural Mozambique 
    Ciampa, Philip J.; Vaz, Lara M.E.; Blevins, Meridith; Sidat, Moshin; Rothman, Russell L.; Vermund, Sten H.; Vergara, Alfredo E. (Indiana University, 2012-05)
    Background: Limited literacy skills are common in the United States (US) and are related to lower HIV knowledge and worse health behaviors and outcomes. The extent of these associations is unknown in countries like ...
  • Understanding the bricks to build better surgical oncology unit at Maputo Central Hospital: prevalent surgical cancers and residents knowledge 
    Morais, Atílio; Come, Jotamo; Selemane, Carlos; Pires, Germano; Tivane, Adriano; Cossa, Matchecane; Tulsidás, Satish; Antunes, Luís; Costa, Manuel João; Sidat, Moshin; Martins, Maria do Rosário; Carrilho, Carla; Santos, Lúcio Lara (Pan African Medical Journal, 2019-02)
    Introduction: cancer is a growing concern in Mozambique. However, the country has limited facilities and few oncologists. Surgical oncologists are an unmet need. The aim of this study was to assess residents' knowledge ...
  • Resisting and tolerating P. falciparum in pregnancy under different malaria transmission intensities 
    Ndam, Nicaise Tuikue; Mbuba, Emmanuel; González, Raquel; Cisteró, Pau; Kariuki, Simon; Kariuki, Simon; Sevene, Esperança; Rupérez, María; Fonseca, Ana Maria; Vala, Anifa; Maculuve, Sonia; Jiménez, Alfons; Quintó, Llorenç; Ouma, Peter; Ramharte, Michael; Aponte, John J.; Nhacolo, Arsenio; Massougbodji, Achille; Briand, Valerie; Kremsner, Peter G.; Mombo-Ngoma, Ghyslain; Desai, Meghna; Macete, Eusebio; Cot, Michel; Menéndez, Clara; Mayor, Alfredo (BMC, 2017)
    Background: Resistance and tolerance to Plasmodium falciparum can determine the progression of malaria disease. However, quantitative evidence of tolerance is still limited. We investigated variations in the adverse impact ...
  • Obstetric fistulae in southern Mozambique: incidence, obstetric characteristics and treatment 
    Mocumbi, Sibone; Hanson, Claudia; Högberg, Ulf; Boene, Helena; Dadelszen, Peter von; Bergström, Anna; Munguambe, Khátia; Sevene, Esperança; The CLIP working group (BioMed Central, 2017)
    Background: Obstetric fistula is one of the most devastating consequences of unmet needs in obstetric services. Systematic reviews suggest that the pooled incidence of fistulae in community-based studies is 0.09 per 1000 ...
  • A public health paradox: the women most vulnerable to malaria are the least protected 
    González, Raquel; Sevene, Esperança; Jagoe, George; Slutsker, Laurence; Menéndez, Clara (PLOS, 2016)
    African HIV-infected pregnant women are the most vulnerable population group to malaria infection. • Paradoxically, these women are also the least protected against malaria due to fear of potential interactions between ...
  • Community health worker knowledge and management of pre-eclampsia in southern Mozambique 
    Boene, Helena; Vidler, Marianne; Augusto, Orvalho; Sidat, Mohsin; Macete, Eusébio; Menéndez, Clara; Sawchuck, Diane; Qureshi, Rahat; Dadelszen, Peter von; Munguambe, Khátia; Sevene, Esperança; The CLIP Feasibility Working Group (2016)
    Background: Mozambique has drastically improved an array of health indicators in recent years, including maternal mortality rates which decreased 63 % from 1990–2013 but the rates still high. Pre-eclampsia and eclampsia ...
  • Changing trends in P. Falciparum burden, immunity, and disease in pregnancy 
    Mayor, Alfredo; Bardají, Azucena; Macete, Eusebio; Nhampossa, Tacilta; Fonseca, Ana Maria; González, Raquel; Maculuve, Sonia; Cisteró, Pau; Rupérez, Maria; Campo, Joe; Vala, Anifa; Sigaúque, Betuel; Jiménez, Alfons; Machevo, Sonia; Fuente, Laura de la; Nhama, Abe; Luis, Leopoldina; Aponte, John J.; Acácio, Sozinho; Nhacolo, Arsenio; Chitnis, Chetan; Dobaño, Carlota; Sevene, Esperança; Alonso, Pedro Luis (2016)
    BACKGROUND Prevention of reinfection and resurgence is an integral component of the goal to eradicate malaria. However, the adverse effects of malaria resurgences are not known. METHODS We assessed the prevalence of ...
  • Prospective observational study to evaluate the clinical safety of the fixed-dose artemisinin-based combination Eurartesim® (dihydroartemisinin/ piperaquine), in public health facilities in Burkina Faso, Mozambique, Ghana, and Tanzania 
    Baiden, Rita; Oduro, Abraham; Halidou, Tinto; Gyapong, Margaret; Sie, Ali; Macete, Eusebio; Abdulla, Salim; Owusu-Agyei, Seth; Mulokozi, Abdunoor; Adjei, Alex; Sevene, Esperanca; Compaoré, Guillaume; Valea, Innocent; Osei, Isaac; Yawson, Abena; Adjuik, Martin; Akparibo, Raymond; Ogutu, Bernhards; Upunda, Gabriel Leonard; Smith, Peter; Binka, Fred (BMC, 2015)
    Background: The World Health Organization recommends artemisinin-based combination (ACT) for the treatment of uncomplicated malaria. Post-licensure safety data on newly registered ACT is critical for evaluating their ...
  • Safety of artemether-lumefantrine exposure in first trimester of pregnancy: an observational cohort 
    Mosha, Dominic; Mazuguni, Festo; Mrema, Sigilbert; Sevene, Esperanca; Abdulla, Salim; Genton, Blaise (BioMed Central, 2014)
    Background: There is limited data available regarding safety profile of artemisinins in early pregnancy. They are, therefore, not recommended by WHO as a first-line treatment for malaria in first trimester due to ...
  • Policy development in malaria vector management in Mozambique, South Africa and Zimbabwe 
    Cliff, Julie; Lewin, Simon; Woelk, Godfrey; Fernandes, Benedita; Mariano, Alda; Sevene, Esperança; Daniels, Karen; Matinhure, Sheillah; Oxman, Andrew; Lavis, John (Oxford University Press, 2019)
    Indoor residual spraying (IRS) and insecticide-treated nets (ITNs), two principal malaria control strategies, are similar in cost and efficacy. We aimed to describe recent policy development regarding their use in ...
  • Multi-country evaluation of safety of dihydroartemisinin/piperaquine post- licensure in african public hospitals with electrocardiograms 
    Kabanywanyi, Abdunoor M.; Baiden, Rita; Ali, Ali M.; Mahende, Muhidin K.; Ogutu, Bernhards R.; Oduro, Abraham; Tinto, Halidou; Gyapong, Margaret; Sie, Ali; Sevene, Esperança; Macete, Eusébio; Owusu-Agyei, Seth; Adjei, Alex; Compaoré, Guillaume; Valea, Innocent; Osei, Isaac; Yawson, Abena; Adjuik, Martin; Akparibo, Raymond; Kakolwa, Mwaka A.; Abdulla, Salim; Binka, Fred (PLOS ONE, 2016)
    The antimalarial drug piperaquine is associated with delayed ventricular depolarization, causing prolonged QT interval (time taken for ventricular de-polarisation and re-polarisa- tion). There is a lack of safety data ...
  • A public health paradox: the women most vulnerable to malaria are the least protected 
    González, Raquel; Sevene, Esperança; Jagoe, George; Slutske, Laurence; Menéndez, Clara (PLOS Medicine, 2016-05-03)
    African HIV-infected pregnant women are the most vulnerable population group to malaria infection. Paradoxically, these women are also the least protected against malaria due to fear of potential interactions between ...
  • Mortality, morbidity, and developmental outcomes in infants born to women who received either mefloquine or sulfadoxine- pyrimethamine as intermittent preventive treatment of malaria in pregnancy: a cohort study 
    Rupérez, María; González, Raquel; Mombo-Ngoma, Ghyslain; Kabanywanyi, Abdunoor M.; Sevene, Esperança; Ouédraogo, Smaı̈lao Aberto; Kakolwa, Mwaka A.; Valá, Anifa; Accrombessi, Manfred; Briand, Valérie; Aponte, John J.; Zoleko, Rella Manego; Adegnika, Ayôla A.; Cot, Michel; Kremsner, Peter G.; Massougbodji, Achille; Abdulla, Salim; Ramharter, Michael; Macete, Eusébio; Menéndez, Clara (PLOS Medicine, 2016-02-23)
    Background: Little is known about the effects of intermittent preventive treatment of malaria in pregnancy (IPTp) on the health of sub-Saharan African infants. We have evaluated the safety of IPTp with mefloquine (MQ) ...
  • Young adolescent girls are at high risk for adverse pregnancy outcomes in sub-Saharan Africa: an observational multicountry study 
    Mombo-Ngoma, Ghyslain; Mackanga, Jean-Rodolphe; González, Raquel; Ouédraogo, Smaı̈la; Kakolwa, Mwaka A.; Manego, Rella Zoleko; Basra, Arti; Rupérez, María; Cot, Michel; Kabanywanyi, Abdunoor M.; Matsiegui, Pierre-Blaise; Agnandji, Seldiji T.; Valá, Anifa; Massougbodji, Achille; Abdulla, Salim; Adegnika, Ayôla A.; Sevene, Esperança; Macete, Eusébio; Yazdanbakhsh, Maria; Kremsner, Peter G.; Aponte, John J.; Menéndez, Clara; Ramharter, Michael (BMJ, 2016-04-14)
    Objectives One of Africa's most important challenges is to improve maternal and neonatal health. The identification of groups at highest risk for adverse pregnancy outcomes is important for developing and implementing ...
  • Community perspectives on the determinants of maternal health in rural southern Mozambique: a qualitative study 
    Firoz, Tabassum; Vidler, Marianne; Makanga, Prestige Tatenda; Boene, Helena; Chiaú, Rogério; Sevene, Esperança; Magee, Laura A.; Dadelszen, Peter von; Munguambe, Khátia; CLIP Working Group (BioMed Central, 2016)
    Background: Mozambique has one of the highest rates of maternal mortality in sub-Saharan Africa. The main influences on maternal health encompass social, economic, political, environmental and cultural determinants ...
  • Barriers and facilitators to health care seeking behaviours in pregnancy in rural communities of southern Mozambique 
    Munguambe, Khátia; Boene, Helena; Vidler, Marianne; Bique, Cassimo; Sawchuck, Diane; Firoz, Tabassum; Makanga, Prestige Tatenda; Qureshi, Rahat; Macete, Eusébio; Menéndez, Clara; Dadelszen, Peter von; Sevene, Esperança (BioMed Central, 2016)
    Background In countries, such as Mozambique, where maternal mortality remains high, the greatest contribution of mortality comes from the poor and vulnerable communities, who frequently reside in remote and rural areas ...
  • Community perceptions of pre-eclampsia and eclampsia in southern Mozambique 
    Boene, Helena; Vidler, Marianne; Sacoor, Charfudin; Nhama, Abel; Nhacolo, Ariel; Bique, Cassimo; Alonso, Pedro L.; Sawchuck, Diane; Qureshi, Rahat; Macete, Eusébio; Menéndez, Clara; Dadelszen, Peter von; Sevene, Esperança; Munguambe, Khátia (BioMed Central, 2016)
    Background Sub-Saharan Africa has the highest maternal mortality ratio at 500 deaths per 100,000 live births. In Mozambique maternal mortality is estimated at 249-480 per 100,000 live births and eclampsia is the third ...
  • The feasibility of community level interventions for pre-eclampsia in South Asia and Sub-Saharan Africa: a mixed-methods design 
    Khowaja, Asif Raza; Qureshi, Rahat; Sawchuck, Diane; Oladapo, Olufemi T.; Adetoro, Olalekan O.; Bellad, Mrutyunjaya; Mallapur, Ashalata; Charantimath, Umesh; Sevene, Esperança; Munguambe, Khátia; Boene, Helena Edith; Vidler, Marianne; Bhutta, Zulfiqar A.; Dadelszen, Peter von; CLIP Working Group (BioMed Central, 2016-06)
    Background: Globally, pre-eclampsia and eclampsia are major contributors to maternal and perinatal mortality; of which the vast majority of deaths occur in less developed countries. In addition, a disproportionate number ...
  • Assessment of the safety of antimalarial drug use during early pregnancy (ASAP): protocol for a multicenter prospective cohort study in Burkina Faso, Kenya and Mozambique 
    Tinto, Halidou; Sevene, Esperança; Dellicour, Stephanie; Calip, Gregory S.; Alessandro, Umberto D’; Macete, Eusébio; Nakanabo-Diallo, Seydou; Kazienga, Adama; Valea, Innocent; Sorgho, Hermann; Valá, Anifa; Augusto, Orvalho; Rupérez, María; Menendez, Clara; Ouma, Peter; Desai, Meghna; Kuile, Feiko Ter; Stergachis, Andy (BioMed Central, 2015)
    A major unresolved safety concern for malaria case management is the use of artemisinin combination therapies (ACTs) in the first trimester of pregnancy. There is a need for human data to inform policy makers and treatment ...
  • Perceptions of malaria in pregnancy and acceptability of preventive interventions among Mozambican pregnant women: implications for effectiveness of malaria control in pregnancy 
    Boene, Helena; González, Raquel; Valá, Anifa; Rupérez, María; Velasco, César; Machevo, Sónia; Sacoor, Charfudin; Sevene, Esperança; Macete, Eusébio; Menéndez, Clara; Munguambe, Khátia (PLOS ONE, 2014)
    Background: Intermittent Preventive Treatment (IPTp) and insecticide treated nets (ITNs) are recommended malaria in pregnancy preventive interventions in sub-Saharan Africa. Despite their cost-effectiveness and seemingly ...

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